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Croda International Plc 2000 dspe peg2000
2000 Dspe Peg2000, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 94/100, based on 441 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 441 article reviews
2000 dspe peg2000 - by Bioz Stars, 2026-02
94/100 stars

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Composition and characterization of the LNPs. (a) Composition of the LNPs (weight percentages of total) (b) Influence of helper lipid (DOPE and DOPC) weight percentages on LNP size. (c) Influence of C14120 weight percentages on size of TPGS and <t>DSPE-PEG</t> containing LNPs. (d) Influence of PEG-lipid (TPGS and DSPE-PEG) weight percentages on LNP size. (e) Change in LNP size upon mRNA loading as a function of TPGS weight percentage (N/P ratio = 12). Data shows Mean+-SD (n = 3).
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Composition and characterization of the LNPs. (a) Composition of the LNPs (weight percentages of total) (b) Influence of helper lipid (DOPE and DOPC) weight percentages on LNP size. (c) Influence of C14120 weight percentages on size of TPGS and <t>DSPE-PEG</t> containing LNPs. (d) Influence of PEG-lipid (TPGS and DSPE-PEG) weight percentages on LNP size. (e) Change in LNP size upon mRNA loading as a function of TPGS weight percentage (N/P ratio = 12). Data shows Mean+-SD (n = 3).
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Croda International Plc glycol 2000 dspe peg2000 avanti polar lipids
Composition and characterization of the LNPs. (a) Composition of the LNPs (weight percentages of total) (b) Influence of helper lipid (DOPE and DOPC) weight percentages on LNP size. (c) Influence of C14120 weight percentages on size of TPGS and <t>DSPE-PEG</t> containing LNPs. (d) Influence of PEG-lipid (TPGS and DSPE-PEG) weight percentages on LNP size. (e) Change in LNP size upon mRNA loading as a function of TPGS weight percentage (N/P ratio = 12). Data shows Mean+-SD (n = 3).
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Composition and characterization of the LNPs. (a) Composition of the LNPs (weight percentages of total) (b) Influence of helper lipid (DOPE and DOPC) weight percentages on LNP size. (c) Influence of C14120 weight percentages on size of TPGS and DSPE-PEG containing LNPs. (d) Influence of PEG-lipid (TPGS and DSPE-PEG) weight percentages on LNP size. (e) Change in LNP size upon mRNA loading as a function of TPGS weight percentage (N/P ratio = 12). Data shows Mean+-SD (n = 3).

Journal: bioRxiv

Article Title: Optimizing C14120-based LNPs for in vitro and in vivo mRNA delivery

doi: 10.1101/2025.09.02.673705

Figure Lengend Snippet: Composition and characterization of the LNPs. (a) Composition of the LNPs (weight percentages of total) (b) Influence of helper lipid (DOPE and DOPC) weight percentages on LNP size. (c) Influence of C14120 weight percentages on size of TPGS and DSPE-PEG containing LNPs. (d) Influence of PEG-lipid (TPGS and DSPE-PEG) weight percentages on LNP size. (e) Change in LNP size upon mRNA loading as a function of TPGS weight percentage (N/P ratio = 12). Data shows Mean+-SD (n = 3).

Article Snippet: 2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE– PEG-2000), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) were purchased from Avanti Polar Lipids.

Techniques:

Cell-type and origin-dependency of in vitro mCherry expression for individual LNPs measured 24 hours post-transfection. (a) Histograms showing mCherry expression in bEnd3 (blue) and AML12 (red) cells upon transfection with LNPs formulated with different types of PEG-lipids (TPGS and DSPE-PEG) in comparison to respective untransfected sample (Ctrl). (b-c) mCherry expression levels, respective of data shown in a), but including a Lipofectamine 2000 (LIPO) transfection control. (c) mCherry expression level as a function of PEG-lipid percentages (DSPE-PEG and TPGS) in ARPE-19, Hep G2, AML12 and HEK293-H. Data are presented as Mean+-SD (n = 3); * p < 0.05 , ** p < 0.01 , *** p < 0.001 . Significance was determined by independent t -test.

Journal: bioRxiv

Article Title: Optimizing C14120-based LNPs for in vitro and in vivo mRNA delivery

doi: 10.1101/2025.09.02.673705

Figure Lengend Snippet: Cell-type and origin-dependency of in vitro mCherry expression for individual LNPs measured 24 hours post-transfection. (a) Histograms showing mCherry expression in bEnd3 (blue) and AML12 (red) cells upon transfection with LNPs formulated with different types of PEG-lipids (TPGS and DSPE-PEG) in comparison to respective untransfected sample (Ctrl). (b-c) mCherry expression levels, respective of data shown in a), but including a Lipofectamine 2000 (LIPO) transfection control. (c) mCherry expression level as a function of PEG-lipid percentages (DSPE-PEG and TPGS) in ARPE-19, Hep G2, AML12 and HEK293-H. Data are presented as Mean+-SD (n = 3); * p < 0.05 , ** p < 0.01 , *** p < 0.001 . Significance was determined by independent t -test.

Article Snippet: 2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE– PEG-2000), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) were purchased from Avanti Polar Lipids.

Techniques: In Vitro, Expressing, Transfection, Comparison, Control